Fig. 2. The irritable bowel syndrome-symptom severity scale (IBS-SSS) scores at 0, 2 and 6 weeks after the administration of solifenacin (visit 1, 2 and 3) and at 4 weeks after the administration of ramosetron (visit 4). (A) Total IBS-SSS scores at 0, 2 and 6 weeks after the administration of solifenacin (visit 1, 2 and 3) and at 4 weeks after the administration of ramosetron, *P < 0.001 as compared with the values at week 0. (B) The score for the severity of pain at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, **P < 0.05 as compared with the values at week 0. (C) The scores for the duration of pain at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, ***P < 0.01 as compared with the values at week 0. (D) The scores for the distension at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, (E) The scores for the satisfaction at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, *P < 0.001 as compared with the values at week 0. (F) The scores for the quality of life at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, *P < 0.001 as compared with the values at week 0. (G) The scores for the frequency of defecation at 2 and 6 weeks after the administration of solifenacin and at 4 weeks after the administration of ramosetron, *P < 0.001 as compared with the values at week 0.
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