Fig. 1. A model structure of the gastric H+, K+-ATPase. The gastric H+, K+-ATPase α subunit has 3 lobes, N (ATP binding), P (phosphorylation) and A (activation) domains in the cytoplasmic domain, and 3 transmembrane segments in the membrane domain. The gastric β subunit has short cytoplasmic region, 1 transmembrane segment, and a heavily glycosylated extracellular region. The number of Asn sites having carbohydrates is based on pig H+, K+-ATPase.
© J Neurogastroenterol Motil
