Fig. 1. A biopsychosocial conceptualization of the pathogenesis and clinical expression of irritable bowel syndrome (IBS). It shows the relationships between psychosocial and physiological factors, IBS symptoms and clinical outcome. CNS, central nervous system; ENS, enteric nervous system; FGID, functional gastrointestinal disorder. MD, medical doctor. Adapted from Drossman.12
© J Neurogastroenterol Motil
