
Comparison of 24-Hour Multichannel Intraluminal Impedance-pH and High-resolution Impedance Manometry Parameter Between Patients Who Had Symptom Improvement on Gastroesophageal Reflux Disease Questionnaire
Parameter | Improvement (n = 11) | No improvement (n = 9) | P-value |
---|---|---|---|
Post-ARMA parameter change | |||
AET |
–1.80 (–3.7, –1.00) | –2.1 (–3.3, 1.2) | 0.909 |
NRE |
–47 (–53.5, –27.5) | –33 (–44, –19) | 0.044 |
MNBI 3cm |
659 (200.5, 937) | –405.5 (–543.5, 225.25) | 0.017 |
MNBI 5cm |
731 (418, 1017.5) | –486.5 (–758.75, 137.25) | 0.008 |
DCI |
152 (40.5, 694.5) | 296 (168, 431) | 0.970 |
EGJ-CI |
8 (–4.5, 18) | 20 (9.25, 34.75) | 0.282 |
LES Resting Pressure |
4 (–1.5, 11.5) | 12 (4, 21.25) | 0.265 |
Pre-ARMA parameters | |||
AET | 3.8 (2.40, 7.1) | 4.4 (4.2, 9.3) | 0.403 |
NRE | 81 (55.00, 85.5) | 79 (53, 86) | 0.97 |
MNBI 3cm | 1690 (1252, 2318) | 1893 (1026, 2539) | 0.953 |
MNBI 5cm | 1730 (1460, 2660) | 2349 (1225, 2820) | 0.937 |
Intact peristalsis | 100 (90, 100) | 50 (40, 80) | 0.042 |
Weak peristalsis | 0 (0, 5) | 30 (0, 40) | 0.03 |
Failed peristalsis | 0 (0, 0) | 10 (0, 30) | 0.078 |
DCI | 1244 (799.5, 1694) | 523 (302, 600) | 0.014 |
EGJ-CI | 12 (9, 18) | 8 (2, 32) | 0.917 |
LES Resting Pressure | 12 (9, 22) | 6 (4, 13) | 0.183 |
aCalculated by subtracting the difference of before and after the anti-reflux mucosal ablation (ARMA) procedure.
AET, acid exposure time; NRE, number of reflux episodes; MNBI, mean nocturnal baseline impedance; DCI, distal contractile integral; EGJ-CI, esophagogastric junction contractile integral; LES, lower esophageal sphincter.
Data are presented as median (interquartile range).