Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 5.

Comparison of 24-Hour Multichannel Intraluminal Impedance-pH and High-resolution Impedance Manometry Parameter Between Patients Who Had Symptom Improvement on Gastroesophageal Reflux Disease Questionnaire

Parameter Improvement (n = 11) No improvement (n = 9) P-value
Post-ARMA parameter change
AETa –1.80 (–3.7, –1.00) –2.1 (–3.3, 1.2) 0.909
NREa –47 (–53.5, –27.5) –33 (–44, –19) 0.044
MNBI 3cma 659 (200.5, 937) –405.5 (–543.5, 225.25) 0.017
MNBI 5cma 731 (418, 1017.5) –486.5 (–758.75, 137.25) 0.008
DCIa 152 (40.5, 694.5) 296 (168, 431) 0.970
EGJ-CIa 8 (–4.5, 18) 20 (9.25, 34.75) 0.282
LES Resting Pressurea 4 (–1.5, 11.5) 12 (4, 21.25) 0.265
Pre-ARMA parameters
AET 3.8 (2.40, 7.1) 4.4 (4.2, 9.3) 0.403
NRE 81 (55.00, 85.5) 79 (53, 86) 0.97
MNBI 3cm 1690 (1252, 2318) 1893 (1026, 2539) 0.953
MNBI 5cm 1730 (1460, 2660) 2349 (1225, 2820) 0.937
Intact peristalsis 100 (90, 100) 50 (40, 80) 0.042
Weak peristalsis 0 (0, 5) 30 (0, 40) 0.03
Failed peristalsis 0 (0, 0) 10 (0, 30) 0.078
DCI 1244 (799.5, 1694) 523 (302, 600) 0.014
EGJ-CI 12 (9, 18) 8 (2, 32) 0.917
LES Resting Pressure 12 (9, 22) 6 (4, 13) 0.183

aCalculated by subtracting the difference of before and after the anti-reflux mucosal ablation (ARMA) procedure.

AET, acid exposure time; NRE, number of reflux episodes; MNBI, mean nocturnal baseline impedance; DCI, distal contractile integral; EGJ-CI, esophagogastric junction contractile integral; LES, lower esophageal sphincter.

Data are presented as median (interquartile range).

J Neurogastroenterol Motil 2025;31:75~85 https://doi.org/10.5056/jnm24055
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