Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 1.

Findings on High-resolution Esophageal Manometry in 57 Patients With Ineffective Esophageal Motility (Based on Chicago Classification Version 4.0 Criteria Applied to 10 Supine Swallows) Who Underwent 3 Multiple Rapid Swallow Sequences

Single swallows Upright Supine P-value
Peristalsis classification No. of swallows
Intact 1 1 0.590
Fragmented 0 0 0.140
Weak 4 5 0.022
Failed 4 2 0.005
DCI (mmHg·s·cm) 221.8 307.4 0.003
IRP (mmHg) 4.7 7.4 0.001
MRS sequence
Post-MRS DCI (mmHg·s·cm)
MRS 1 192 0.450
MRS 2 172
MRS 3 80
Mean post-MRS DCI (mmHg·s·cm) 241
Contraction reserve Upright Supine
MRS sequence No. 1 26 (45.6) 23 (40.4) 0.180
MRS sequence No. 2 29 (50.9) 22 (38.6) 0.008
MRS sequence No. 3 18 (31.6) 15 (26.3) 0.320
2 MRS sequencesa 37 (64.9) 31 (54.4) 0.013
3 MRS sequencesa 39 (68.4) 33 (57.9) 0.034
Mean post-MRS DCI 32 (56.1) 22 (38.6) 0.004

aRepresents presence of contraction reserve after 2 and 3 multiple rapid swallows (MRS) sequences defined as any post-MRS distal contraction integral (DCI) > single swallow DCI.

IRP, integrated relaxation pressure.

Contraction reserve was assessed referencing the post-MRS DCI to single upright and supine swallows.

Data are presented as median or n (%).

J Neurogastroenterol Motil 2025;31:38~44 https://doi.org/10.5056/jnm24097
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