Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

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Fig. 2. Management of refractory gastroesophageal reflux disease (GERD). Lifestyle adjustments are useful in any patient with reflux symptoms. Antisecretory therapy should be optimized and escalated if indicated. Adjunctive and topical agents, as well as adjunctive measures can be employed to improve symptoms. In patients with objective evidence of refractory GERD, escalation of management to anti-reflux surgery or other invasive interventions may be appropriate. H2RA, histamine H2 receptor antagonist; PPI, proton pump inhibitor; PCAB, potassium competitive acid blocker; G-POEM, gastric peroral endoscopic myotomy.
J Neurogastroenterol Motil 2024;30:17~28
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