Fig. 3. Forrest plot of studies comparing the efficacy of antibiotics in irritable bowel syndrome (IBS) patients with or without small intestinal bacterial overgrowth (SIBO). The pooled response rate was 51.2% vs 23.4% in the SIBO and no SIBO group, respectively. Relative risk (95% CI) for improvement was 2.07 (1.40-3.08),
P = 0.0003. Heterogeneity was
I2 = 0.01%,
P = 0.300.
