Fig. 1. Study Schema. GERDQ, gastroesophageal reflux disease questionnaire; QoLRAD, Quality of Life in Reflux and Dyspepsia; PPI, proton pump inhibitor; GI, gastrointestinal; HRM, high-resolution manometry; 24-hr MII-pH, 24-hour multichannel intraluminal impedance-pH; ERD A/B, erosive reflux disease grade A and B; ERD C/D, erosive reflux disease grade C and D; NERD, nonerosive reflux disease; RH, reflux hypersensitivity; FH, functional heartburn; HC, healthy controls; qRT-PCR, quantitative real-time polymerase chain reaction; ELISA, enzyme-linked immunosorbent assay.
© J Neurogastroenterol Motil
