Fig. 6. Effect of berberine and rifaximin on microglial activation in spinal cords. (A) Representative images of Iba-1-stained microglia in the dorsal lumbar spinal cord. (B) Number of Iba-1-positive cells in the dorsal lumbar spinal cord. (C-G) Morphological parameters of microglia. GH, germ-free (GF) rats receiving fecal microbiota transplantation (FMT) from healthy control; GI, GF rats receiving FMT from irritable bowel syndrome patients; GIBBR, GI rats receiving berberine treatment; GIR, GI rats receiving rifaximin treatment. n = 4/group. *P < 0.05, **P < 0.01.
© J Neurogastroenterol Motil
