Fig. 4. Effect of berberine and rifaximin on fecal concentrations of short chain fatty acids (SCFAs). (A-F) The fecal concentration of the 6 SCFAs. (G) Heat map of the Spearman’s rank correlation coefficient between the 6 SCFAs and selected genera. GH, germ-free (GF) rats receiving fecal microbiota transplantation (FMT) from healthy control, n = 5; GI, GF rats receiving FMT from irritable bowel syndrome patients, n = 8; GIBBR, GI rats receiving berberine treatment, n = 8; GIR, GI rats receiving rifaximin treatment, n = 7. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
© J Neurogastroenterol Motil
