Fig. 3. Comparison of changes of selected genera in the berberine- and rifaximin-treated groups. (A-D) The relative abundance of representative genera. (E) Correlation network of genus-genus interactions. GH, germ-free (GF) rats receiving fecal microbiota transplantation (FMT) from healthy control, n = 5; GI, GF rats receiving FMT from irritable bowel syndrome patients, n = 8; GIBBR, GI rats receiving berberine treatment, n = 8; GIR, GI rats receiving rifaximin treatment, n = 7. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
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