Intercellular Space Values of Healthy Control, Gastroesophageal Reflux Disease Phenotypes and Functional Heartburn
| Groups | HC | Mild ERD | Severe ERD | NERD | RH | FH |
|---|---|---|---|---|---|---|
| n | 15 | 58 | 17 | 25 | 15 | 19 |
| Mean (µm) | 0.98 | 1.22 |
1.35 |
0.98 | 0.96 | 1.02 |
| SD (µm) | 0.23 | 0.25 | 0.24 | 0.31 | 0.27 | 0.29 |
| Median (µm) | 1.01 | 1.22 | 1.29 | 0.95 | 0.99 | 0.97 |
| Minimum (µm) | 0.54 | 0.54 | 0.89 | 0.52 | 0.46 | 0.62 |
| Maximum (µm) | 1.38 | 1.69 | 1.68 | 1.54 | 1.37 | 1.47 |
Bonferroni multiple comparison: amild erosive reflux disease (ERD) vs healthy control (HC) (P = 0.036), nonerosive reflux disease (NERD) (P = 0.004), reflux hypersensitivity (RH) (P = 0.014), bsevere ERD vs HC (P = 0.002), NERD (P < 0.001), RH (P = 0.001), functional heartburn (FH) (P = 0.004).