Fig. 6. Distribution of differentially expressed genes (DEGs) and functional analysis. (A) The volcano plot of DEGs. Each point represents a gene. Green and red dots represent downregulated and upregulated DEGs, respectively. (B) Heatmap of the DEGs. The horizontal and vertical axes represent the samples (achalasia, red; control, blue) and DEGs (red, upregulated; blue, downregulated), respectively. (C) Histogram of Gene Ontology (GO) classification of DEGs. (D) The chord diagram of GO analysis. (E) The Bubble Chart of DEGs Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment results. (F) Cnetplot in DEGs KEGG pathway enrichment results. BP, biological process; CC, cellular component; MF, molecular function; P. adjust, P. adjust value; TRP, transient receptor potential ion channels.
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