High-resolution Manometry Findings Between Chicago Classification Versions 3.0 and 4.0 in Patients With Esophagogastric Junction Outflow Obstruction
| HRM findings | CC v3.0 (n = 41) | Diagnosis-changed |
CC v4.0 (n = 26) | |
|---|---|---|---|---|
| Supine IRP (mmHg) | 27.0 (25.0-31.0) | 26.0 (25.0-31.0) | 28.5 (25.0-31.1) | 0.909 |
| Supine DCI (mmHg·s·cm) | 1612.0 (870.0-2323.0) | 1389.0 (631.0-2349.0) | 1754.5 (1172.8-2328.3) | 0.803 |
| Supine DL (sec) | 7.4 (6.8-9.0) | 8.0 (7.0-9.0) | 7.0 (6.0-9.0) | 0.057 |
| Upright IRP (mmHg) | 24.0 (19.0-29.5) | 23.0 (17.0-33.0) | 24.5 (20.0-28.3) | 0.786 |
| Upright DCI (mmHg·s·cm) | 1310.0 (520.0-2007.5) | 1310.0 (521.0-2207.0) | 1317.5 (460.5-1863.5) | 0.891 |
| Upright DL (sec) | 7.2 (6.4-8.3) | 8.0 (7.0-8.0) | 7.0 (6.0-8.0) | 0.468 |
| MRS-IRP (mmHg) |
24.0 (17.5-30.0) | 24.0 (21.0-32.0) | 23.5 (16.8-28.5) | 0.701 |
| MRS-DCI (mmHg·s·cm) |
861.0 (387.0-2371.5) | 1092.0 (372.0-2391.0) | 842.5 (412.5-2366.3) | 0.975 |
| RDC-IRP (mmHg) |
20.1 (16.0-24.0) |
22.0 (16.0-27.0) | 20.5 (13.5-23.8) |
> 0.999 |
aDiagnosis changed from esophagogastric junction outflow obstruction (EGJOO) to normalcy.
bIntegrated relaxation pressure (IRP) during multiple rapid swallows (MRS).
cDistal contractile integral (DCI) during MRS.
dIRP during rapid drink challenge (RDC).
en = 39.
fn = 24.
HRM, high-resolution manometry; CC v3.0, Chicago classification version 3.0; CC v4.0, Chicago classification version 4.0; DL, distal latency.
Data are presented as median (interquartile range).