Fig. 4. Comparison of type 3 small-conductance calcium-activated potassium current density in platelet-derived growth factor receptor alpha-positive (PDGFRα+) cells from normal and diabetic mice dialysed with 500 nM calcium ion (Ca2+) pipette solution. (A) Representative current traces in response to step depolarizations in normal PDGFRα+ cells with 500 nM Ca2+ pipette solution. (B) Representative current traces of diabetic PDGFRα+ cells dialyzed with 500 nM Ca2+ pipette solution when exposed to step depolarizations. (C) Summary of net outward current density in PDGFRα+ cells from normal (black line) and streptozotocin (STZ)-treated mice (red line). (D) Summarized data of net outward current density at +70 mV in PDGFRα+ cells from normal and STZ-treated mice. Data are shown as the mean ± SEM (n = 4; *P < 0.05).
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