Journal of Neurogastroenterology and Motility

Table. 3. Table 3

Gene Ontology Terms From the Interstitial Cells of Cajal-expressed Proteins That Overlap With the Bulk RNA-sequencing Expressed Genes and Interstitial Cells of Cajal Single-cell RNA-sequencing Marker Genes

GO ID	Term	Benjamin P-value
GO:0030036	Actin cytoskeleton organization	2.67E-07
GO:0007015	Actin filament organization	1.42E-05
GO:0070252	Actin-mediated cell contraction	1.29E-04
GO:0006937	Regulation of muscle contraction	7.46E-04
GO:0007517	Muscle organ development	2.32E-03
GO:0043270	Positive regulation of ion transport	2.32E-03
GO:0014706	Striated muscle tissue development	2.32E-03
GO:0030049	Muscle filament sliding	2.98E-03
GO:0051146	Striated muscle cell differentiation	3.80E-03
GO:0016477	Cell migration	4.37E-03
GO:0055002	Striated muscle cell development	4.37E-03
GO:0031032	Actomyosin structure organization	5.17E-03
GO:0000902	Cell morphogenesis	5.17E-03
GO:0055001	Muscle cell development	5.17E-03
GO:0048468	Cell development	5.95E-03
GO:0006941	Striated muscle contraction	5.95E-03
GO:0010959	Regulation of metal ion transport	6.65E-03
GO:0042692	Muscle cell differentiation	1.08E-02
GO:1904062	Regulation of cation transmembrane transport	1.46E-02
GO:0048513	Animal organ development	1.65E-02
GO:0046716	Muscle cell cellular homeostasis	1.65E-02
GO:0072358	Cardiovascular system development	1.96E-02
GO:0072359	Circulatory system development	1.96E-02
GO:0030334	Regulation of cell migration	2.10E-02
GO:0051271	Negative regulation of cellular component movement	2.32E-02
GO:2000145	Regulation of cell motility	2.82E-02
GO:0051017	Actin filament bundle assembly	3.08E-02
GO:0045055	Regulated exocytosis	3.08E-02
GO:0010927	Cellular component assembly involved in morphogenesis	3.21E-02
GO:0043269	Regulation of ion transport	4.47E-02

GO, gene ontology.

Terms related to interstitial cells of Cajal functions are highlighted in gray.

J Neurogastroenterol Motil 2023;29:238~249 https://doi.org/10.5056/jnm22078