Fig. 3. Forest plot of studies showing prevalence of small intestinal bacterial overgrowth (SIBO) in systemic sclerosis-patients and controls, stratified according to mode of diagnosis of SIBO (OR, 9.6; 95% CI, 5.6-16.5; P < 0.001), (I2 = 0.00%, P = 0.798). The odds ratio for SIBO in SSc-patients compared to controls utilizing jejunal aspirate and culture (JAC) is 9.0 (95% CI, 2.7-30.4; P < 0.001), (I2 = 0.00%, P = 0.985), utilizing lactulose breath test (LBT) is 12.0 (95% CI, 6.1-23.6; P < 0.001), (I2 = 0.00%, P = 0.404), utilizing glucose breath test (GBT) is 4.1 (95% CI, 1.0-16.3; P = 0.041), (I2 = 0.00%, P > 0.999).
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