Fig. 6. Transcripts encoding Toll-like receptor 2 (Tlr2) are downregulated in the proximal colon of stressed mice and correlated with levels of transcripts encoding genes involved in enteric nervous system (ENS) function. Quantitative real-time polymerase chain reaction was used to analyze Tlr2 and Tlr4 expression levels in small intestine and colon of control and stressed mice (n = 10/group). Transcripts encoding Tlr2 were downregulated in the proximal colon of stressed mice. The increase expression levels of Tlr4 in proximal and distal colon of stressed mice did not reach statistical significance. Data represent mean ± SEM.**P < 0.01 by Mann Whitney test.
© J Neurogastroenterol Motil
