Fig. 2. Effects of adenosine triphosphate (ATP) treatment in the human colon segment. The contractility of the colonic segments was reduced after 300 µM ATP administration in both the right (A) and left colon (C). The frequency and area under the curve (AUC) in the right colonic segment significantly decreased after 300 µM ATP administration in the circular muscle (CM) and longitudinal muscle (LM) (B). The frequency and AUC in the left colonic segment significantly decreased after 300 µM ATP administration in the CM and LM (D). Control, before 300 µM ATP; Amp, amplitude after 300 µM ATP; Freq, frequency after 300 µM ATP; AUC, area under the curve after 300 µM ATP; Rt, right; Lt, left. *P < 0.05.
© J Neurogastroenterol Motil
