Fig. 6. Slow-wave and spike-burst activity during cyclic peristalsis. (A) Spatiotemporal transverse strain maps which shows the regularly occurring propagating contractions of cyclic peristalsis. (B, C) Activation maps of spike-burst and slow-wave activity during the peristaltic contraction indicated by the solid arrow in (A). The shaded area represents the position of the intestine on the electrode array. The black rectangle in (B) indicate the field of view of the camera. (D) Electrical signal traces from a row of electrodes in (B, C), where red crosses indicate slow-wave events. The solid arrow indicates the spike-burst propagation shown in (B). The dash arrows show propagating spike-bursts from 2 slow-wave pacemakers that gave rise to the back-and-forth propagating contraction indicated with the dashed arrows in (A). Cyclic peristaltic contractions were caused by longitudinally propagating spike-burst patches that were associated with slow-waves as seen in (D). The spike-bursts activated periodically with the slow-waves causing propagating circumferential contractions at the frequency of the slow-waves. The spatiotemporal activation of slow-waves and spike-bursts during cyclic peristalsis is shown in video form in
Supplementary Video 3.
