Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

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Fig. 4. Alpha and beta diversity of responders and non-responders. The microbial diversity of the (A-C) pre-treatment and (D-F) post-treatment samples are shown. The alpha diversity using the (A, D) Chao1 and (B, E) Shannon indices are depicted as boxplots, whereas (C, F) the beta diversity based on the Bray-Curtis dissimilarity are depicted as principal coordinate analysis plots. The Chao1 and Shannon indices did not demonstrate any significant differences between the responder and non-responder groups before (A, B) and after (D, E) probiotic treatment (P = 0.248, 0.729, 0.291, and 0.429). The permutational multivariate analysis of variance also did not demonstrate any significant differences in beta diversity before and after treatment (P = 0.885 and P = 0.626, respectively) (C, F). PC, principal component.
J Neurogastroenterol Motil 2022;28:642~654
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