Journal of Neurogastroenterology and Motility

Table. 4. Table 4

Median Values for Subjects in the 2 Protocols With Normosensitivity Versus Hypersensitivity, and Gastrointestinal Symptoms (Gastrointestinal Symptom Rating Scale Scores) and Anxiety and Depression (Hospital Anxiety and Depression Scale Scores)

Variable	Protocol 1 Hypersensitivity	Protocol 1 Normosensitivity	P-value
Overall GI symptoms	3 (2-4)	3 (2-3)	0.001^a
Pain	4 (3-4)	3 (2-4)	0.001^a
Bloating	4 (3-5)	3 (3-4)	0.010^a
Diarrhea	3 (2-4)	3 (1-4)	0.020^a
Constipation	3 (2-4)	2 (2-4)	0.123
Satiety	2 (1-3)	1 (1-2)	0.014^a
Anxiety	8 (5-12)	6 (4-10)	< 0.001^a
Depression	5 (2-8)	4 (2-7)	0.192

Variable	Protocol 1 Hypersensitivity	Protocol 1 Normosensitivity	P-value
Variable	Protocol 2 Hypersensitivity	Protocol 2 Normosensitivity	P-value
Overall GI symptoms	3 (3-4)	3 (3-4)	0.293
Pain	4 (4-6)	4 (3-5)	0.032^a
Bloating	5 (4-6)	4 (3-5)	0.255
Diarrhea	4 (3-5)	3 (2-4)	0.054
Constipation	2 (1-4)	3 (1-4)	0.412
Satiety	2 (1-4)	2 (1-4)	0.483
Anxiety	10 (7-11)	8 (4-11)	0.011^a
Depression	5 (2-9)	5 (2-7)	0.338

^aIndicates a P-value ≤ 0.05.

Data are presented as median (interquartile range: 25th, 75th).

J Neurogastroenterol Motil 2022;28:630~641 https://doi.org/10.5056/jnm21214