Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 3.

Comparison of Reflux Parameters Between Patients With and Without Transient Hiatal Separation and Hiatal Hernia

Characteristics Non-hiatal separation
(n = 31)
Transient hiatal separation
(n = 19)
Hiatal hernia
(n = 35)
P-value
Time reflux pH < 4 (%)
Total 0.8 (0.5, 2.3) 1.6 (0.9, 2.4) 2.5 (1.3, 5.8) 0.016a
Upright 1.3 (0.6, 3.3) 2.2 (1.3, 3.5) 4.4 (2.3, 7.5) 0.009a
Recumbent 0.0 (0.0, 0.1) 0.0 (0.0, 0.1) 0.0 (0.0, 0.1) 0.256
Number of acid reflux episodes
Total 17.0 (6.0, 33.0) 22.0 (15.0, 30.0) 33.0 (12.0, 45.0) 0.145
Upright 16.0 (5.0, 30.0) 22.0 (15.0, 30.0) 32.0 (10.0, 42.0) 0.154
Recumbent 0.0 (0.0, 1.0) 0.0 (0.0, 1.0) 0.0 (0.0, 3.0) 0.324
Longest acid reflux episode (min)
Total 2.6 (1.8, 4.0) 4.1 (1.4, 5.4) 5.3 (3.1, 10.8) 0.024a
Upright 2.6 (1.8, 3.9) 4.1 (1.4, 5.4) 5.3 (3.1, 9.0) 0.022a
Recumbent 0.0 (0.0, 1.1) 0.0 (0.0, 0.5) 0.0 (0.0, 3.6) 0.244
DeMeester score 3.4 (1.8, 7.5) 4.7 (3.5, 7.9) 8.4 (3.9, 16.7) 0.016a
Number of reflux events
Total
Acid 19.0 (9.0, 26.0) 26.0 (11.0, 37.0) 25.0 (13.0, 37.0) 0.144
Weakly acid 34.0 (14.0, 56.0) 20.0 (10.0, 45.0) 23.0 (16.0, 32.0) 0.303
Weakly alkaline 1.0 (0.0, 7.0) 0.0 (0.0, 1.0) 0.0 (0.0, 4.0) 0.145
Liquid 14.0 (5.0, 24.0) 11.0 (6.0, 25.0) 14.0 (8.0, 22.0) 0.968
Mixed 42.0 (25.0, 65.0) 41.0 (28.0, 63.0) 40.0 (28.0, 50.0) 0.638
Upright
Acid 19.0 (7.0, 26.0) 26.0 (11.0, 36.0) 25.0 (12.0, 36.0) 0.152
Weakly acid 30.0 (10.0, 52.0) 19.0 (10.0, 45.0) 19.0 (14.0, 28.0) 0.399
Weakly alkaline 1.0 (0.0, 7.0) 0.0 (0.0, 1.0) 0.0 (0.0, 3.0) 0.153
Liquid 12.0 (5.0, 21.0) 10.0 (5.0, 24.0) 11.0 (6.0, 18.0) 0.997
Mixed 42.0 (24.0, 64.0) 41.0 (28.0, 63.0) 37.0 (25.0, 50.0) 0.692
Recumbent
Acid 0.0 (0.0, 0.0) 0.0 (0.0, 1.0) 0.0 (0.0, 2.0) 0.268
Weakly acid 1.0 (0.0, 5.0) 0.0 (0.0, 3.0) 1.0 (0.0, 5.0) 0.336
Weakly alkaline 0.0 (0.0, 0.0) 0.0 (0.0, 0.0) 0.0 (0.0, 0.0) 0.983
Liquid 1.0 (0.0, 4.0) 1.0 (0.0, 2.0) 1.0 (0.0, 6.0) 0.710
Mixed 1.0 (0.0, 2.0) 1.0 (0.0, 1.0) 1.0 (0.0, 2.0) 0.781

aIndicated statistically significant between non-hiatal separation and hiatal hernia groups.

Statistical significance among these three groups was assessed by Kruskal-Wallis test with post-hoc analysis via Dunn’s test.

Data are presented as median (interquartile range: Q1, Q3) or n (%).

J Neurogastroenterol Motil 2022;28:589~598 https://doi.org/10.5056/jnm21189
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