High-resolution Manometric Metrics Among Patients With and Without Transient Hiatal Separation During Straight Leg Raise and Hiatal Hernia
| Characteristics | Non-hiatal separation (n = 31) |
Transient hiatal separation (n = 19) |
Hiatal hernia (n = 35) |
|
|---|---|---|---|---|
| EGJ-CI | 39.0 (26.0, 55.0) | 37.0 (22.0, 62.0) | 31.0 (16.0, 54.0) | 0.212 |
| LES resting pressure | 30.9 (20.6, 43.5) | 29.1 (19.7, 43.1) | 22.0 (12.9, 36.2) | 0.085 |
| IRP-4s (mmHg) | 9.8 (4.7, 12.6) | 10.2 (4.3, 14.9) | 8.5 (2.8, 13.7) | 0.651 |
| DCI (mmHg∙sec∙cm) | 602.0 (204.0, 1030.0) | 1012.0 (478.0, 1205.0) | 524.0 (180.0, 917.0) | 0.126 |
| Ineffective (%) | 50.0 (0.0, 90.0) | 0.0 (0.0, 50.0) | 50.0 (10.0, 80.0) | 0.035 |
| Failed (%) | 10.0 (0.0, 40.0) | 0.0 (0.0, 20.0) | 0.0 (0.0, 50.0) | 0.247 |
| Premature (%) | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) | 0.541 |
| Fragmented (%) | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) | 1.000 |
| Distal latency (sec) | 6.8 (6.1, 7.7) | 6.9 (6.2, 8.1) | 7.2 (6.4, 8.2) | 0.192 |
| Peristaltic breaks (cm) | 2.0 (0.3, 8.3) | 0.9 (0.2, 2.8) | 1.2 (0.3, 6.7) | 0.747 |
| Largest break (cm) | 1.4 (0.1, 3.9) | 0.7 (0.2, 2.3) | 1.0 (0.2, 5.8) | 0.926 |
| MRS response | 24 (82.2) | 18 (94.7) | 22 (64.7) | 0.030 |
aIndicated statistically significant between transient hiatal separation and hiatal hernia groups by Dunn’s test.
Statistical significance among these three groups was assessed by Kruskal-Wallis test with post hoc analysis via Dunn’s test.
EGJ-CI, esophagogastric junction contractile integral; LES, lower esophageal Sphincter; IRP-4s, 4 seconds integrated relaxation pressure; MRS, multiple rapid swallow.
Data are presented as median (interquartile range: Q1, Q3) or n (%).