Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 1.

Demographics, Symptoms, and Symptom Outcome of All Participants

Characteristics Total
(N = 177)		 AET < 4%
(n = 55)		 4% ≤ AET ≤ 6%
(n = 69)		 AET > 6%
(n = 53)		 P-value AET ≥ 4%
(n = 122)		 P-value
Demographics
Age (yr) 49.8 ± 11.5 46.5 ± 10.4 52.1 ± 11.9a 50.3 ± 11.4 0.023 51.3 ± 11.7 0.009
Male 100 (56.5) 23 (41.8) 39 (56.5) 38 (71.7)b 0.007 77 (63.1) 0.008
BMI (kg/m2) 22.8 ± 3.3 22.0 ± 3.8 23.3 ± 3.0 23.0 ± 3.0 0.070 23.2 ± 3.0 0.024
Smoking 36 (20.3) 11 (20.0) 9 (13.0) 16 (30.2) 0.066 25 (20.5) 0.940
Drinking 30 (17.0) 9 (16.4) 12 (17.4) 9 (17.0) 0.989 21 (17.2) 0.889
Symptoms
GerdQ (total) 8.2 ± 2.5 7.9 ± 2.6 7.9 ± 2.4 8.8 ± 2.4 0.104 8.3 ± 2.4 0.352
GerdQ (NERD) 8.1 ± 2.4 7.9 ± 2.7 7.9 ± 2.2 8.6 ± 2.4 0.317 8.2 ± 2.3 0.569
Symptom outcome
PPI response 107 (60.5) 20 (36.4) 48 (69.6)a 39 (73.6)b < 0.001 87 (71.3) < 0.001

aP < 0.05 for acid exposure time (AET) < 4% and 4% ≤ AET ≤ 6%.

bP < 0.05 for AET < 4% and AET > 6%.

BMI, body mass index; GerdQ, gastroesophageal reflux disease questionnaire; NERD, non-erosive reflux disease; PPI, proton pump inhibitor.

Data are presented as mean ± SD or n (%).
J Neurogastroenterol Motil 2022;28:580~588 https://doi.org/10.5056/jnm21156
© J Neurogastroenterol Motil