Fig. 2. Case examples of functional lumen imaging probe (FLIP) panometry and high-resolution manometry (HRM). The FLIP panometry (left) and swallow from HRM study (right) from the 4 patients (A-D) labeled in
Figure 1 are displayed. (A) Patient (HRM/Chicago classification version 4.0 (CCv4.0) diagnosis was type I achalasia) was treated with per-oral endoscopic myotomy (POEM) with significant symptomatic improvement; an Eckardt score was 1 at follow-up. (B) Patient (HRM/CCv4.0 diagnosis was absent contractility) was treated with proton pump inhibitor (PPI) for gastroesophageal reflux. (C) Patient (HRM/CCv4.0 diagnosis of type I achalasia), who also completed timed barium esophagram (TBE) with 13 cm column height at 5 minutes, was treated with POEM with symptom improvement; an Eckardt score was 0 at follow-up. (D) Patient (HRM/CCv4.0 diagnosis of normal motility) completed a TBE, which was normal, and was treated with PPI and dietary modification. Figure used with permission from the Esophageal Center of Northwestern.