Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 5.

Risk Factors Associated With Normal Integrated Relaxation Pressure (< 26 mmHg) in Treatment-naive Achalasia Patients

Variables Univariate analysis Multivariate analysis
OR (95% CI) P-value OR (95% CI) P-value
Sex (male) 1.220 (1.010-1.460) 0.038 1.270 (1.040-1.550) 0.020
Age at onset (≥ 40 yr) 1.350 (1.120-1.620) 0.002 1.530 (1.220-1.920) < 0.001
Age at diagnosis (≥ 65 yr) 1.350 (1.080-1.6800) 0.008 0.980 (0.748-1.280) 0.886
Disease duration (≥ 10 yr) 1.810 (1.460-2.240) < 0.001 1.880 (1.480-2.380) < 0.001
Eckardt score ≥ 4 0.758 (0.579-0.993) 0.045 0.753 (0.546-1.040) 0.084
BMI (≥ 25 kg/m2) 1.500 (1.160-1.940) 0.002 1.430 (1.080-1.890) 0.012
Type I achalasia 2.690 ( 2.210-3.270) < 0.001 2.710 (2.200-3.340) < 0.001
Calcium channel blocker use 0.987 (0.641-1.520) 0.951
Nitrite use 1.750 (0.675-4.510) 0.250
Esophageal dilation (≥ II) 1.340 (1.110-1.620) 0.002 1.060 (0.860-1.310) 0.569
Type of achalasia (sigmoid) 2.120 (1.650-2.720) < 0.001 1.570 (1.200-2.070) 0.001

Esophageal dilation: the grade of esophageal dilation based on maximum transverse diameter (d) using barium esophagogram. Grade I: d < 3.5 cm, grade II: 3.5 cm ≤ d < 6.0 cm, grade III: d ≥ 6.0 cm.

BMI, body mass index.

J Neurogastroenterol Motil 2022;28:562~571 https://doi.org/10.5056/jnm21254
© J Neurogastroenterol Motil