Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 4.

Characteristics of Treatment-naive Achalasia Patients With Normal and Above the Cutoff Integrated Relaxation Pressure Values

Variables IRP < 26 mmHg IRP ≥ 26 mmHg P-value
Sex (male) 423 (53.1%) 496 (48.2%) 0.042
Age at onset (≥ 40 yr) 446 (56.0%) 500 (48.6%) 0.002
Age at diagnosis (≥ 65 yr) 201 (25.3%) 206 (20.0%) 0.009
Disease duration (≥ 10 yr) 246 (30.9%) 204 (19.8%) < 0.001
Eckardt score (≥ 4) 675 (84.8%) 905 (88.0%) 0.045
BMI (≥ 25 kg/m2) 141 (17.7%) 129 (12.5%) 0.002
Type I achalasia 557 (72.1%) 484 (48.5%) < 0.001
Calcium channel blocker use 39 (12.6%) 60 (12.5%) >0.999
Nitrite use 6 (1.9%) 16 (3.3%) 0.276
Esophageal dilation (≥ II) 492 (61.8%) 562 (54.7%) 0.002
Type of achalasia (sigmoid) 182 (22.9%) 126 (12.3%) < 0.001

Missing values of Eckardt score: 52. Calcium channel blocker use and nitrite use are analyzed in 798 patients and 796 patients, respectively. Esophageal dilation: the grade of esophageal dilation based on maximum transverse diameter (d) using barium esophagogram. Grade I: d < 3.5 cm, grade II: 3.5 cm ≤ d < 6.0 cm, grade III: d ≥ 6.0 cm.

IRP, integrated relaxation pressure; BMI, body mass index.

Data are presented as n (%).

J Neurogastroenterol Motil 2022;28:562~571 https://doi.org/10.5056/jnm21254
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