Fig. 1. Bile acids (BAs) synthesis, enterohepatic circulation, and factors affecting BA profiles. BA synthesis could be affected by conditions (eg, decreased in cirrhosis). Small intestinal bacterial overgrowth (SIBO) elevates level of unconjugated BAs in the small intestine. Dysbiosis, BA malabsorption, and rapid gut transit could be associated with increased fecal primary BAs. BSH, bile salt hydrolase.
© J Neurogastroenterol Motil
