Fig. 1. The mechanism of short chain fatty acids (SCFAs) in irritable bowel syndrome (IBS). The metabolites of gut microbiota SCFAs can modulate intestinal epithelial immunity and inflammation, maintain gut barrier integrity, alter gut motility, and act as part of the microbiota-gut-brain axis, which may underlie the potential mechanisms of SCFAs in the pathogenesis of IBS.
© J Neurogastroenterol Motil
