Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Predictor Variables by Irritable Bowel Syndrome Onset. Sample Divided by Prior Psychiatric Disorder

Categorical variables No prior psychiatric disorder (n = 109 914) Prior psychiatric disorder (n = 23 008) P-value
No IBS (n = 108 823) IBS (n = 1091) P-value No IBS (n = 22 592) IBS (n = 416)
Female sex 53.8% 76.0% < 0.001 64.8% 79.3% < 0.001
2 or more prior psychiatric disorders NA -NA 27.7% 35.3% 0.001
Gallstones 2.9% 5.7% < 0.001 4.1% 7.0% 0.004
3 or more allergies 7.7% 13.4% < 0.001 10.5% 11.8% 0.400
Asthma/inhaler 9.7% 15.9% < 0.001 12.0% 15.4% 0.035
Fibromyalgia 1.8% 7.1% < 0.001 4.2% 7.9% < 0.001
PPI 5.8% 12.6% < 0.001 9.5% 16.1% < 0.001
General health:
I seem to get sick a little easier than other people 2.9% 7.8% < 0.001 7.4% 14.4% < 0.001
My health is not good 7.6% 14.8% < 0.001 17.5% 25.7% < 0.001
4 or more GP visits in last year 1.3% 2.4% 0.003 1.2% 1.9% 0.173
Zero doctor visits in the past 5 yr 9.3% 3.4% < 0.001 4.3% 2.6% 0.092
Continuous variables
BMI 26.0 (4.2) 25.89 (4.4) 0.830 26.3 (4.6) 25.5 (4.5) 0.001
Life events and difficulties score 2.4 (1.7) 2.8 (1.7) < 0.001 3.3 (1.7) 3.51 (1.6) 0.022
SCL somatization score 15.5 (3.7) 17.4 (4.7) < 0.001 17.9 (5.3) 19.1 (5.0) < 0.001
PSQI score 3.7 (2.1) 4.4 (2.4) < 0.001 4.6 (2.5) 5.6 (3.0) < 0.001
General health perception −0.06 (0.6) −0.2 (0.6) < 0.001 −0.27 (0.6) −0.42 (0.7) < 0.001
Bodily pain 0.5 (0.7) 0.1 (0.9) < 0.001 0.20 (0.9) 0.016 (0.9) < 0.003
High scorers on continuous variables
SCLsom top quartile 19.9% 37.9% < 0.001 40.7% 53.6% < 0.001
PSQI top quartile 34.6% 53.2% < 0.001 47.1% 67.5% < 0.001
Body pain top quartile 22.4% 37.1% < 0.001 38.5% 43.6% 0.003
General health top quartile 14.4% 23.5% < 0.001 26.7% 38.0% < 0.001

IBS, irritable bowel syndrome; NA, not applicable; PPI, proton pump inhibitor; GP, general practitioner; BMI, body mass index; SCL, Symptom Checklist; PSQI, Pittsburgh Sleep Quality Index.

Data are presented as % or mean (SD).

J Neurogastroenterol Motil 2022;28:442~453 https://doi.org/10.5056/jnm21041
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