Fig. 5. Effect of the serotonin transporter gene-linked long polymorphic region (SLC6A4 5-HTTLPR) gene polymorphism on the severity of epigastric pain in patients with overlap syndrome. Early satiation and epigastric pain symptoms in the non-overlap functional gastrointestinal disorder (FGID) group were not related to the SLC6A4 5-HTTLPR genotype (A, C). In the overlap FGID group, L/L and L/S genotypes elicited more severe symptoms than the S/S genotype (B, D). L, long allele of the SLC6A4 5-HTTLPR gene; S, short allele of the SLC6A4 5-HTTLPR gene; f/u, follow-up.
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