Fig. 4. Changes in severity of upper gastrointestinal symptoms during the follow-up period according to the serotonin transporter gene-linked long polymorphic region (SLC6A4 5-HTTLPR) gene polymorphism. Early satiation (A) and postprandial fullness (C) were most severe in patients with the SLC6A4 5-HTTLPR L/S genotype and were found to worsen. Epigastric pain symptoms (B) in patients with the SLC6A4 5-HTTLPR L/L genotype were maintained and did not deteriorate or improve. L, long allele of the SLC6A4 5-HTTLPR gene; S, short allele of the SLC6A4 5-HTTLPR gene; f/u, follow-up.
© J Neurogastroenterol Motil
