Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Subject Characteristics of the Case and Control Groups at Baseline (Categorical Parameters)

Characteristics Case group Control group P-valuea
N n (%) N n (%)
Male 2066 1558 (75.4) 4132 3116 (75.4) 1.000
Current drinking 1925 1379 (71.6) 3838 2680 (69.8) 0.156
Amount of alcohol 1392 2740 < 0.001
< 20 g/day 652 (46.8) 1418 (51.8)
20-40 g/day 442 (31.8) 872 (31.8)
40-60 g/day 240 (17.2) 344 (12.6)
≥ 60 g/day 58 (4.2) 106 (3.9)
Current smoking 1923 471 (24.5) 3838 821 (21.4) 0.008
Symptoms
Acid reflux symptoms 2057 239 (11.6) 4117 192 (4.7) < 0.001
Gastric pain 1627 90 (5.5) 3259 166 (5.1) 0.517
Heavy stomach 1358 136 (10.0) 2715 234 (8.6) 0.144
Feeling of fullness 1244 106 (8.5) 2487 167 (6.7) 0.046
Belching 1137 75 (6.6) 2273 116 (5.1) 0.074
Abdominal pain 488 24 (4.9) 976 46 (4.7) 0.863
Endoscopic findings
Hiatal hernia 1960 458 (23.4) 3916 492 (12.6) < 0.001
Atrophic gastritis 1960 693 (35.4) 3917 1637 (41.8) < 0.001
Barrett’s esophagus 1960 53 (2.7) 3916 127 (3.2) 0.258
Comorbidities
Diabetes 2022 174 (8.6) 4040 294 (7.3) 0.068
Hypertension 2022 417 (20.6) 4040 704 (17.4) 0.003
Hyperlipidemia 2022 351 (17.4) 4040 620 (15.4) 0.044
H. pylori infection 33 13 (39.4) 87 46 (52.9) 0.187

aP-values were calculated using chi-square test.

N, total number of subjects in the group (except subjects whose characteristics were unknown); H. pylori, Helicobactor pylori.

J Neurogastroenterol Motil 2022;28:86~94 https://doi.org/10.5056/jnm20237
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