Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Multichannel Intraluminal Impedance-pH and Hypopharyngeal Multichannel Intraluminal Impedance Measurements

MII-pH measurements Subjects P-value
Total (n = 21) MII-pH ON PPI (n = 8) MII-pH OFF PPI(n = 13)
Reflux events
Distal reflux 55 (36-72) 64.5 (56-83) 51 (28-69) 0.166
Proximal reflux 23 (11-39) 31 (18-47) 15 (7-29) 0.057
AET 0.7 (0.2-1.1) 0.8 (0.1-1.3) 0.7 (0.3-1.1) 0.986
AET > 6% 0/21 (0) 0/8 (0) 0/13 (0)
AET 4-6% 1/21 (5) 1/8 (13) 0/13 (0)
AET < 4% 20/21 (95) 7/8 (87) 13/13 (100)
Symptom index
Positive for EES 1/21 (5) 1/8 (13) 0/13 (0)
Positive for typical symptom 4/21 (19) 1/8 (13) 3/13 (23)
Symptom association probability
Positive for EES 2/19 (11) 2/7 (29) 0/12 (0)
Positive for typical symptom 2/19 (11) 1/7 (14) 1/12 (8)
HMII measurements
Reflux events
Distal reflux 54.5 (46.5-66.5) 58.5 (45.5-73.5) 54.0 (47.0-65.0) 0.276
FCR 6.0 (5.5-17.0) 10.0 (6.0-17.5) 6.0 (2.0-13.5) 0.287
LPR 0.0 (0.0-1.5) 0.0 (0.0-2.5) 0.0 (0.0-1.5) 0.898
Positive APE 17/21 (81) 8/8 (100) 9/13 (69) 0.131
AET 6.0 (1.5-10.6) 6.1 (3.2-9.2) 3.9 (1.0-11.2) 0.683
Symptom Index
Positive for EES 5/21 (24) 3/8 (38) 2/13 (15)
Positive for typical symptom 6/21 (29) 3/8 (38) 3/13 (23)
Symptom association probability
Positive for EES 3/21 (14) 2/8 (25) 1/13 (8)
Positive for typical symptom 6/21 (29) 3/8 (38) 3/13 (23)

MII-pH, multichannel intraluminal impedance-pH; AET, acid exposure time; EES, extraesophageal symptoms; HMII, hypopharyngeal multichannel intraluminal impedance; FCR, full column reflux; LPR, laryngopharyngeal reflux; APE, abnormal proximal exposure.

J Neurogastroenterol Motil 2022;28:69~77 https://doi.org/10.5056/jnm20228
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