Strength of Recommendation and Quality of Evidence
| Strength of recommendation | Position |
| Strong | Most patients should receive the recommended course of action. |
| Conditional | Different choices would be appropriate for different patients. |
| Quality of evidence | Definition |
| High | We are very confident that the true effect lies close to the estimate of the effect. |
| Moderate | We are moderately confident in the effect estimate. The true effect is likely to be close to the estimate of effect, but there is a possibility that it is substantially different. |
| Low | Our confidence in the estimate is limited. The true effect may be substantially different from the estimate of effect. |
| Very low | We have very little confidence in the effect estimate. The true effect is likely to be substantially different from the estimate of effect. |