Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 4.

The Preoperative Reflux and Postoperative Reflux/Non-reflux Group

Variables Preoperative reflux and postoperative reflux group (n = 19) Preoperative reflux and postoperative non-reflux group (n = 44) P-value
Gender (male/female) 11/8 24/20 0.806
Age (yr) 41.58 ± 12.60 43.25 ± 15.30 0.677
BMI (kg/m2) 22.70 (18.90-25.60) 20.88 (18.59-23.65) 0.206
Before POEM
Total Eckardt scores 5 (4-6) 5 (4-7) 0.538
HRM
Length of esophageal (cm) 28.00 ± 1.80 27.90 ± 2.50 0.839
LESP (mmHg) 37.10 ± 14.10 39.20 ± 15.50 0.649
UESP (mmHg) 77.60 ± 28.98 64.20 ± 28.60 0.120
IRP (mmHg) 29.40 ± 11.79 32.30 ± 12.20 0.398
Subtypes
Type I 4 (21.1) 4 (9.1)
Type II 15 (78.9) 39 (88.6)
Type III 0 (0.0) 1 (2.3) 0.466
POEM
Tunnel length (cm) 14.00 (12.00-15.00) 13.00 (12.00-14.00) 0.230
Myotomy length (cm) 11.00 (10.00-12.00) 11.00 (9.00-12.00) 0.299
After POEM
Total Eckardt scores 2 (1-5) 1 (0-1) < 0.01
GERDQ 7 (7-8) 6 (6-6) < 0.01
HRM variables Preoperative reflux and postoperative reflux group (n = 8) Preoperative reflux and postoperative non-reflux group (n = 14) P-value
Length of esophageal (cm) 27.76 ± 2.05 26.89 ± 2.67 0.432
LESP (mmHg) 17.38 ± 3.33 17.68 ± 5.81 0.894
UESP (mmHg) 65.63 ± 16.20 48.75 ± 26.87 0.152
IRP (mmHg) 13.01 ± 2.70 12.46 ± 4.17 0.74
△Eckardt scores 1.7 ± 2.3 4.3 ± 1.8 < 0.01
△LESP (mmHg) 12.55 (3.35-14.88) 16.55 (7.90-48.00) 0.082
△IRP (mmHg) 16.10 (5.20-22.80) 18.10 (10.35-24.10) 0.330

BMI, body mass index; POEM, peroral esophageal myotomy; HRM, high-resolution manometry; LESP, lower esophageal sphincter pressure; UESP, upper esophageal sphincter pressure; IRP, integrated relaxation pressure; GERDQ, gastroesophageal reflux disease questionnaire; △Eckardt score = preoperative Eckardt score - postoperative Eckardt score; △LESP = preoperative LESP - postoperative LESP; △IRP = preoperative IRP - postoperative IRP.

Values are presented as n, mean ± SD, median (interquartile range), or n (%).

J Neurogastroenterol Motil 2021;27:377~389 https://doi.org/10.5056/jnm20041
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