Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 3.

The Reflux/Non-reflux Group After Peroral Esophageal Myotomy

Variables Reflux group (n = 25) Non-reflux group (n = 59) P-value
Gender (male/female) 12/13 30/29 0.811
Age (yr) 44.61 ± 15.77 41.40 ± 11.57 0.303
BMI (kg/m2) 22.20 (19.50-24.50) 21.50 (18.70-23.90) 0.594
Before POEM
Regurgitation
Absent 6 (24.0) 15 (25.4)
Present 19 (76.0) 44 (74.6) 0.890
Total Eckardt scores 5 (4-6) 5 (3-5) 0.825
HRM
Length of esophageal (cm) 27.20 ± 2.35 27.37 ± 2.60 0.802
LESP (mmHg) 34.50 (27.40-48.10) 35.20 (28.15-44.25) 0.745
UESP (mmHg) 71.30 (60.00-97.75) 64.40 (39.45-83.05) 0.083
IRP (mmHg) 31.20 ± 11.50 29.10 ± 10.60 0.457
Subtypes
Type I 4 (16.0) 5 (8.5)
Type II 21 (84.0) 53 (89.8)
Type III 0 (0.0) 1 (1.7) 0.595
POEM
Tunnel length (cm) 14.00 (12.25-15.00) 13.00 (12.00-14.00) 0.153
Myotomy length (cm) 11.55 ± 1.90 10.70 ± 2.30 0.158
After POEM
Total Eckardt scores (range) 3 (2-4) 1 (0-1) < 0.01
GERDQ 7 (7-8) 6 (6-6) < 0.01
HRM variables Reflux group (n = 13) Non-reflux group (n = 19) P-value
Length of esophageal (cm) 26.90 ± 2.20 27.10 ± 2.70 0.851
LESP (mmHg) 21.03 ± 7.35 17.10 ± 7.20 0.137
UESP (mmHg) 71.40 ± 19.10 53.96 ± 23.68 0.042a
IRP (mmHg) 14.90 ± 3.50 12.70 ± 5.20 0.201
△Eckardt scores 2 (–0.5-3) 4 (2-5) < 0.01
△LESP (mmHg) 12.30 (2.45-16.75) 17.15 (12.88-35.15) 0.030a
△IRP (mmHg) 13.10 ± 9.15 17.60 ± 6.57 0.139

aP < 0.05.

BMI, body mass index; POEM, peroral esophageal myotomy; HRM, high-resolution manometry; LESP, lower esophageal sphincter pressure; UESP, upper esophageal sphincter pressure; IRP, integrated relaxation pressure; GERDQ, gastroesophageal reflux disease questionnaire; △Eckardt score = preoperative Eckardt score - postoperative Eckardt score; △LESP = preoperative LESP - postoperative LESP; △IRP = preoperative IRP - postoperative IRP.

Values are presented as n, mean ± SD, median (interquartile range), or n (%).

J Neurogastroenterol Motil 2021;27:377~389 https://doi.org/10.5056/jnm20041
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