Fig. 1. Immunohistochemical expression of tight junction (TJ) protein complex in unaffected colonic mucosa of symptomatic uncomplicated diverticular disease (SUDD) patients and controls (control group [CG]). Immunohistochemical expression of TJ protein complex (claudin and zonulin) was lower in the colonic healthy mucosa of 16 SUDD patients compared to 16 CG subjects. Bars in the graphic represents the median average score of immunohistochemical positivity calculated in 3 ×100 field for each sample using an ImageJ plugin. Box plots represent median, 25%-75% interquartile range and minimum-maximum values. Original magnification: ×100; high power field: ×200. Scale bars, 250 µm and 100 µm.
© J Neurogastroenterol Motil
