Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Comparison of the Findings of 24-Hour Multichannel Intraluminal Impedance-pH Monitoring Test With the Hill Grade on Endoscopy

Variable Hill grade 1
(n = 56)
Hill grade 2
(n = 22)
Hill grade 3
(n = 16)
Hill grade 4
(n = 11)
P-valuea
Acid exposure index (%) 0.4 (0.1-0.9) 1.6 (0.2-2.7) 3.6 (1.5-7.9) 4.2 (3.3-11.5) < 0.001
Number of pH reflux episodes (episode) 7.1 (1.2-12.8) 16.6 (6.0-23.4) 20.9 (7.4-37.6) 35.1 (20.0-48.4) < 0.001
Number of pH reflux episodes > 5 min (episode) 0.0 (0.0-0.0) 1.0 (0.0-1.9) 1.6 (0.3-3.0) 5.2 (0.4-9.8) < 0.001
Mean acid clearance time (sec) 26.0 (11.8-57.3) 86.0 (27.3-166.8) 106.5 (83.0-238.8) 190.0 (67.0-233.0) < 0.001
DeMeester score 1.3 (0.9-2.8) 5.2 (1.9-10.8) 9.9 (3.8-19.1) 13.3 (7.7-32.6) < 0.001
Number of reflux episodes (episode)
Total 28.0 (14.8-40.0) 45.5 (26.0-57.5) 49.5 (33.2-79.3) 90.0 (46.0-124.0) < 0.001
Acid 9.0 (3.0-18.8) 20.0 (8.5-38.0) 25.5 (9.0-42.8) 43.0 (33.0-78.0) < 0.001
Weakly acidic 14.0 (7.0-22.0) 19.0 (12.3-35.0) 19.0 (6.0-27.8) 20.0 (15.0-70.0) 0.048
Weakly alkaline 0.0 (0.0-1.0) 0.0 (0.0-1.0) 0.0 (0.0-0.8) 0.0 (0.0-2.0) 0.720
Number of gastroesophageal reflux reaching proximal extent (episode)
Total 12.0 (6.3-19.8) 21.5 (12.3-39.0) 23.5 (14.3-52.2) 33.0 (24.0-70.0) < 0.001
Acid 5.0 (1.0-10.8) 13.5 (4.0-26.3) 15.0 (6.0-30.0) 25.0 (11.0-57.0) < 0.001
Weakly acidic 6.0 (2.0-10.0) 10.5 (4.0-18.0) 7.5 (2.0-12.8) 11.0 (5.0-24.0) 0.010
Weakly alkaline 0.0 (0.0-0.0) 0.0 (0.0-0.3) 0.0 (0.0-0.0) 0.0 (0.0-1.0) 0.459
Bolus exposure index (%) 0.8 (0.3-1.1) 1.1 (0.8-1.9) 1.6 (0.8-2.3) 2.3 (1.6-4.4) < 0.001
Mean bolus clearance time (sec) 12.0 (9.0-15.8) 14.0 (10.8-17.3) 13.5 (8.5-18.5) 13.0 (9.0-18.0) 0.371

aPerformed with the Kruskal-Wallis test.

Values are presented as median (interquartile range).

J Neurogastroenterol Motil 2021;27:191~197 https://doi.org/10.5056/jnm20033
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