Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 4.

Comparison of Pre- and Post-treatment Parameters in Groups of Patients With and Without Partial Peristaltic Recovery After Peroral Endoscopic Myotomy

Assessed pre- and post-POEM parameters No peristaltic recovery
(n = 167)
Peristaltic recovery
(n = 47)
Mean difference P-valuea P-valueb


Mean ± SD Mean ± SD
Age (yr) 46.9 ± 14.9 47.2 ± 14.7 –0.348 0.433 0.907
IRP pre (mmHg) 27.8 ± 13.5 33.3 ± 12.4 –5.498 0.003 0.051
IRP post (mmHg) 13.0 ± 5.7 14.7 ± 5.5 –1.737 0.039 0.130
IRP red (mmHg) 14.8 ± 12.9 18.6 ± 12.6 –3.777 0.013 0.159
Eckardt score pre 7.1 ± 2.1 7.0 ± 1.8 0.039 0.459 0.925
Eckardt score post 0.4 ± 0.8 0.3 ± 0.6 0.125 0.141 0.392
Eckardt score red 6.6 ± 2.2 6.7 ± 1.9 –0.115 0.311 0.786
LESP pre (mmHg) 40.8 ± 18.9 46.3 ± 14.6 –5.485 0.010 0.154
LESP post (mmHg) 23.2 ± 9.9 23.2 ± 9.4 –0.018 0.412 0.993
LESP red (mmHg) 17.5 ± 19.1 23.5 ± 15.7 –6.044 0.009 0.128
TBE 5 min pre (cm) 8.2 ± 4.1 7.6 ± 4.2 0.595 0.261 0.549
TBE 5 min post (cm) 1.3 ± 2.5 1.4 ± 2.7 –0.021 0.295 0.968
TBE 5 min red (cm) 6.9 ± 4.9 5.9 ± 4.5 1.062 0.153 0.369
TBE width pre (cm) 3.9 ± 1.3 3.4 ± 1.3 0.506 0.025a 0.097
TBE width post (cm) 2.6 ± 0.9 2.6 ± 1.9 0.048 0.027a 0.850

IRP, integrated relaxation pressure; LESP, lower esophageal sphincter pressure; pre, before peroral endoscopic myotomy (POEM); post, after POEM; red, delta of the pre- and post-POEM value (ie, reduction after POEM) TBE 5 min, height of the column at 5 minutes on timed barium esophagogram, width.

aP-values obtained from Mann–Whitney U test. P < 0.05 is considered significant.

bLogistic regression showed no predictive factors of the peristaltic recovery among the analyzed parameters.

J Neurogastroenterol Motil 2021;27:205~214 https://doi.org/10.5056/jnm20126
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