Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Serum Brain-derived Neurotrophic Factor Levels of the Participants at Baseline and Endpoint

Time of measure Probiotic (n = 28) Prebiotic (n = 25) Placebo (n = 25) P-value
Baseline (ng/mL) 0.392 (0.346-0.445) 0.425 (0.367-0.492) 0.483 (0.419-0.558) 0.090
Endpoint (ng/mL) 0.483 (0.424-0.548) 0.389 (0.335-0.453) 0.467 (0.401-0.542) 0.090a
< 0.001b
∆BDNF (ng/mL) 0.095 –0.056 0.009 < 0.001
(0.056-0.134) (–0.096- –0.010) (–0.047- –0.039) Partial etasquare0.262

aNot adjusted and badjusted for baseline values.

∆BDNF, change from baseline.

Data for serum brain-derived neurotrophic factor (BDNF) levels were log transformed and then back transformed to display as mean (95% CI).

P-value is based on ANOVA/ANCOVA test. P < 0.05 is considered significant. Partial eta squared is an effect size measure for one-way or factorial ANOVA.

J Neurogastroenterol Motil 2020;26:486~495 https://doi.org/10.5056/jnm20079
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