Journal of Neurogastroenterology and Motility

Table. 2. Table 2

Serum Brain-derived Neurotrophic Factor Levels of the Participants at Baseline and Endpoint

Time of measure	Probiotic (n = 28)	Prebiotic (n = 25)	Placebo (n = 25)	P-value
Baseline (ng/mL)	0.392 (0.346-0.445)	0.425 (0.367-0.492)	0.483 (0.419-0.558)	0.090
Endpoint (ng/mL)	0.483 (0.424-0.548)	0.389 (0.335-0.453)	0.467 (0.401-0.542)	0.090^a
				< 0.001^b
∆BDNF (ng/mL)	0.095	–0.056	0.009	< 0.001
	(0.056-0.134)	(–0.096- –0.010)	(–0.047- –0.039)	Partial etasquare0.262

^aNot adjusted and ^badjusted for baseline values.

∆BDNF, change from baseline.

Data for serum brain-derived neurotrophic factor (BDNF) levels were log transformed and then back transformed to display as mean (95% CI).

P-value is based on ANOVA/ANCOVA test. P < 0.05 is considered significant. Partial eta squared is an effect size measure for one-way or factorial ANOVA.

J Neurogastroenterol Motil 2020;26:486~495 https://doi.org/10.5056/jnm20079