Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 3.

Childhood Factors and Development of Irritable Bowel Syndrome

Study Population  IBS diagnosis Methodology Sample size Risk factors
Walker et al,27 1993, USA GI clinic (adults) Physician-diagnosed IBS Prospective dataRecollection 28 Severe Childhood sexual abuse
Talley et al,28 1994, USA Survey (adults) Self Questionnaire BDQ Prospective dataRecollection 130 Childhood abuse
Mendall and Kumar,20 1998, UK GP clinic (adults) Self Questionnaire Manning  Prospective dataRecollection 48  Antibiotic use Privileged childhood living conditions
Talley et al,29 1998 Australia Voters (adults) Self Questionnaire  BSQ Prospective data Recollection 90 Childhood abuse
Salmon et al,22 2003, UK Clinic visits (adults) Self Questionnaire + Physician Prospective dataRecollection 64 Childhood sexual, physical and psychological abuse
Howell et al,21 2004 Australia Birth Registry Self Questionnaire BSQ Longitudinal Birth Cohort 157 Affluent childhood environment
Dong et al,25 2005, China Students Self Questionnaire Rome II Prospective data collection 716 Anxiety, depression, introverted, food habits (excessive pepper), personal habits (smoking/alcoholism), bad exterior environment (abdominal operation, abuse of antibiotics, exposure to coldness, and fatigue), single parent
Son et al,30 2009, S Korea Females students Self Questionnaire Rome II Prospective data collection 104 Higher stress, anxiety, and depression
Beesley et al,23 2010, UK Clinic visits (adults) Physician Rome III Prospective data Recollection 75 Childhood sexual abuse A tendency to suppress anger, anxious
Tietjen et al,24 2010, USA Clinic visits (adults) Self-report + Physician Prospective data Recollection 418 emotional abuse
Zhou et al,31 2012, China Students Interview Questionnaire less Prospective data collection 268 Poor sleep
Koloski et al,12 2015, Australia Survey responders (adults) Self Questionnaire Rome I Prospective data Recollection 130 Sharing bedroom to 5 years oldExposure to herbivore pet (horse/bird) to 5 years old
Adeniyi et al,19 2017 Nigeria Students Self Questionnaire, Rome III Prospective data collection  62 Lower socioeconomic statusPast history of gastroenteritis
Tan et al,32 2017, Taiwan National Health Insurance Research Database Physician-diagnosed IBS Retrospective 11 242 Antecedent allergic diseases, allergic rhinitis, higher clinical allergy burden.
Rajindrajith et al,33 2018, Sri Lanka Students Self Questionnaire, Rome III Prospective data collection 1972 Exposure to physical, emotional and sexual abuse
Tan et al,26 2019, Taiwan National Health Insurance Research Database Physician-diagnosed IBS Retrospective 3537 Air pollutants

IBS, irritable bowel syndrome; GI, gastrointestinal; GP, general practitioner; BDQ, Bowel Disease Questionnaire; BSQ, Bowel Screening Questionnaire.

J Neurogastroenterol Motil 2020;26:437~446 https://doi.org/10.5056/jnm20109
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