Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 2.

Parental Factors and Development of Irritable Bowel Syndrome

Study Population  IBS diagnosis Methodology Sample size Risk factors Protective factors
Hislop,17 1979, Australia Medical records Physician-diagnosed IBS Recollection 333 Childhood parental deprivation (parental loss, alcoholic, unsatisfactory relationships)
Levy et al,13 2001, USA Population –Twins Self Questionnaire Prospective data collection 6060 Mother/father with IBS  
Lackner et al,15 2004, USA Clinic referrals Self Questionnaire Rome II + Physician Prospective data collection 81 Paternal parenting behaviors (rejection or hostility)
Xing et al,14 2014, China School students Self Questionnaire Rome III Prospective data collection 96 Parental punishment, Paternal rejection, Maternal over-interference, Paternal overprotection Parental emotional warmth
Knight et al,18 2015, USA Medical records Self QuestionnaireTalley Nested Case-control 287 Family history of mental illness/alcohol, substance abuse problems
van Tilburg et al,16 2015, USA Clinic visits Self QuestionnaireRome I Retrospective 296 Mothers with psychological traits (anxiety, depression, and somatization), Family stress
Waehrens et al,10 2018, Sweden Swedish Birth Registry ICD Codes – Record Review Longitudinal Birth Cohort 24 633 Young maternal age < 20 years old, Maternal marital status (divorced/widowed), Maternal education of 10-14 years old, Parental history of IBS, anxiety, depression ≥ 35 years old maternal delivery

IBS, irritable bowel syndrome; ICD, International Classification of Diseases.

J Neurogastroenterol Motil 2020;26:437~446 https://doi.org/10.5056/jnm20109
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