Fig. 4. Correlations between structural factors of Hamilton Depression Rating Scale and the efficacy of neuromodulators in patients with irritable bowel syndrome with diarrhea. (A) The baseline mental disorders score negatively correlated with improvements in emotions. (B, C) The scores of anxiety/somatization and retardation symptoms positively correlated with improvement in diarrhea after paroxetine therapy. (D, E) The baseline sleep disturbances score positively correlated with improvements in defecation-related abdominal pain/discomfort and diarrhea after mirtazapine therapy.
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