Fig. 3. Effects of external Na⁺-free, Ca²⁺-free or flufenamic acid (FFA) on pacemaker activity in small intestinal interstitial cells of Cajal. (A) Application of Na⁺-free solution abolished the generation of pacemaker activity. (B) Application of Ca²⁺-free solution abolished the generation of pacemaker activity. (C) Application of FFA (50 μM) abolished the generation of pacemaker activity.

J Neurogastroenterol Motil 2020;26:521~528 https://doi.org/10.5056/jnm20064

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