Fig. 3. Effects of external Na+-free, Ca2+-free or flufenamic acid (FFA) on pacemaker activity in small intestinal interstitial cells of Cajal. (A) Application of Na+-free solution abolished the generation of pacemaker activity. (B) Application of Ca2+-free solution abolished the generation of pacemaker activity. (C) Application of FFA (50 μM) abolished the generation of pacemaker activity.
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