Fig. 1. Effects of ML204 (an inhibitor of transient receptor potential canonical [TRPC] 4/5 channels) or englerin A (EA; a selective activator of TRPC4/5 channels) on pacemaker activity in small intestinal interstitial cells of Cajal (ICCs). (A) Pacemaker potentials of ICCs under current-clamp mode in control condition and ML204 (10 μM) action. (B) Pacemaker potentials of ICCs under current-clamp mode in control condition and EA action on pacemaker potentials.
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