Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Table. 3.

Multivariate Logistic Regression Analysis of Predictors of Proton Pump Inhibitors Non-response

Predictors of PPIs non-response OR (95% CI) P-value
AET < 6% 2.5 (1.2-5.0) 0.011
Number of reflux episodes 1.3 (0.6-2.9) 0.608
MNBI 3 cm > 2292 Ω 2.7 (1.0-6.1) 0.047
MNBI 5 cm > 2292 Ω 2.4 (1.0-5.6) 0.046
EGJ-CI > 39.1 mmHg∙cm 3 (1.3-7.1) 0.012
Type I EGJ 1.8 (1.0-3.4) 0.047
IEM 1.8 (0.7-5.2) 0.225
Fragmented peristalsis 0.5 (0.2-1.6) 0.324
Absent peristalsis 0.7 (0.4-2.7) 0.778

PPIs, proton pump inhibitors; AET, acid exposure time; MNBI, mean nocturnal baseline impedance; EGJ-CI, esophagogastric junction contractile integral; IEM, ineffective esophageal motility.

J Neurogastroenterol Motil 2020;26:447~454 https://doi.org/10.5056/jnm19153
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