Esophageal Physiologic Test Results in Responders and Non-responders
| Esophageal physiologic test variables | Non-responders |
Responders |
|
|---|---|---|---|
| MII-pH | |||
| AET (%) | 4.2 (1.3) | 7.8 (2.4) | 0.034 |
| Upright AET (%) | 6.2 (2.1) | 6.7 (2.3) | 0.225 |
| Supine AET (%) | 2.1 (0.9) | 9.0 (3.4) | 0.003 |
| Reflux episodes | 51 (17) | 64 (23) | 0.344 |
| MNBI 3 cm (Ω) | 2108 (412) | 1607 (235) | 0.027 |
| MNBI 5 cm (Ω) | 2057 (436) | 1654 (258) | 0.024 |
| HRM |
23.7 (3.3) | 20.4 (2.8) | 0.033 |
| EGJ-CI (mmHg∙cm) | 30 (4.2) | 22 (2.1) | 0.011 |
| IRP (mmHg) | 8.2 (1.5) | 7.7 (1.2) | 0.448 |
| DCI (mmHg∙cm∙sec) | 1641 (158) | 1236 (116) | 0.029 |
| Absent peristalsis | 7 (7%) | 8 (8%) | 0.789 |
| DES | 1 (1%) | 0 (0.%) | 0.884 |
| Fragmented peristalsis | 10 (9%) | 5 (5%) | 0.278 |
| IEM | 11 (10%) | 15 (15%) | 0.402 |
| Normal peristalsis | 76 (73%) | 71 (72%) | 0.896 |
MII-pH, multichannel intraluminal impedance pH; AET, acid exposure time; MNBI, mean nocturnal baseline impedance; HRM, high-resolution manometry; LES, lower esophageal sphincter; EGJ-CI, esophagogastric junction contractile integral; IRP, integrated relaxation pressure; DCI, distal contractile integral; DES, distal esophageal spasm; IEM, ineffective esophageal motility.
Data are presented as mean (SD) or number (%).