Fig. 2. Luminal concentration of 5-hydroxytryptamine (5-HT) of the duodenum during migrating motor complex cycle. During duodenal phase I, the luminal concentration of 5-HT of the duodenum is 29 ng/mL, which is significantly increased to 59 ng/mL during the duodenal phase II. Luminal concentration of 5-HT of the duodenum is further increased to 250 ng/mL during phase III. In contrast to the duodenum, luminal concentration of 5-HT of the stomach is not significantly changed during phase I, II and III. Open squares indicate phase II contractions and closed squares indicate phase III contractions. Adapted from Nakajima et al.61
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